Mulvihill, D.P. and Win, T.Z. and Pack, T.P. and Hyams, J.S. (2000) Cytokinesis in fission yeast: a myosin pas de deux. Microsc Res Tech, 49 (2). pp. 152-60. ISSN 1059-910X .
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Cytokinesis in the fission yeast, Schizosaccharomyces pombe consists of two distinct but overlapping events: the assembly and constriction of a cytokinetic actomyosin ring (CAR) and the formation of a cross wall or septum. These two processes must be spatially and temporally coordinated both with each other and with other cell cycle events, most notably spindle formation and anaphase chromosome segregation. In fission yeast, the CAR contains two unusual type II myosins, Myo2, encoded by the gene myo2(+), and Myp2, encoded by myp2(+). The relationship of these two proteins to each other and their relative contribution to CAR assembly and contraction is largely unknown. Here we review what is known about the role of each myosin in cytokinesis and present some new information concerning their regulation and possible physical interaction.
|Additional information:||1059-910X (Print) Journal Article Research Support, Non-U.S. Gov't Review|
|Uncontrolled keywords:||Actins/metabolism Carrier Proteins/genetics/*metabolism Cell Cycle Proteins/metabolism *Cell Division Fungal Proteins/genetics/*metabolism Gene Expression Regulation, Fungal Models, Biological *Myosin Heavy Chains *Myosin Type II *Myosin Type V Myosins/genetics/*metabolism Protein-Serine-Threonine Kinases/metabolism *Saccharomyces cerevisiae Proteins Schizosaccharomyces/*cytology/genetics/physiology *Schizosaccharomyces pombe Proteins|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Biosciences|
|Depositing User:||Dan Mulvihill|
|Date Deposited:||01 Jun 2009 07:53|
|Last Modified:||14 Jan 2010 14:32|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/8908 (The current URI for this page, for reference purposes)|
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