Candida albicans HSP12 is co-regulated by physiological CO2 and pH

Sheth, Chirag C. and Mogensen, Estelle G. and Fu, Man Shun and Blomfield, Ian C. and Mühlschlegel, Fritz A. (2008) Candida albicans HSP12 is co-regulated by physiological CO2 and pH. Fungal Genetics and Biology, 45 (7). pp. 1075-1080. ISSN 1087-1845 . (The full text of this publication is not available from this repository)

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Abstract

Global transcriptional analysis of Candida albicans exposed to elevated ambient CO(2) revealed a statistically significant differential regulation of 14 genes. Subsequent RNA hybridisation analysis of one gene, HSP12, confirmed CO(2)-regulation via a cAMP-dependent mechanism. Additionally, Northern analyses and gel mobility shift assays demonstrate the co-regulation of HSP12 by environmental pH via a Rim101-dependent mechanism.

Item Type: Article
Additional information: 1096-0937 (Electronic) Journal article
Uncontrolled keywords: Candida albicans; CO2; microarray; HSP12; EMSA; pH; transcriptional regulation
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences > Biomedical Research Group
Depositing User: F.A.M. Muhlschlegel
Date Deposited: 13 Mar 2009 10:37
Last Modified: 12 May 2014 10:50
Resource URI: http://kar.kent.ac.uk/id/eprint/6198 (The current URI for this page, for reference purposes)
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