Making an escape: development and function of the Drosophila giant fibre system

Allen, M.J. and Godenschwege, T.A. and Tanouye, M.A. and Phelan, P. (2006) Making an escape: development and function of the Drosophila giant fibre system. Semin Cell Dev Biol, 17 (1). pp. 31-41. ISSN 1084-9521. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1016/j.semcdb.2005.11.011

Abstract

Flies escape danger by jumping into the air and flying away. The giant fibre system (GFS) is the neural circuit that mediates this simple behavioural response to visual stimuli. The sensory signal is received by the giant fibre and relayed to the leg and wing muscle motorneurons. Many of the neurons in the Drosophila GFS are uniquely identifiable and amenable to cell biological, electrophysiological and genetic studies. Here we review the anatomy and development of this system and highlight its utility for studying many aspects of nervous system biology ranging from neural development and synaptic plasticity to the aetiology of neural disorder.

Item Type: Article
Additional information: 1084-9521 (Print) Journal Article
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences > Cell & Developmental Biology Group
Depositing User: Marcus J Allen
Date Deposited: 02 Sep 2008 23:21
Last Modified: 14 Jan 2010 14:21
Resource URI: http://kar.kent.ac.uk/id/eprint/5870 (The current URI for this page, for reference purposes)
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