The mRNA cap-binding protein eIF4E in post-transcriptional gene expression

von der Haar, Tobias and Gross, John D. and Wagner, Gerhard and McCarthy, John E. G. (2004) The mRNA cap-binding protein eIF4E in post-transcriptional gene expression. Nature Structural and Molecular Biology, 11 (6). pp. 503-511. ISSN 1545-9985. (Full text available)

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http://dx.doi.org/10.1038/nsmb779

Abstract

Eukaryotic initiation factor 4E (eIF4E) has central roles in the control of several aspects of post-transcriptional gene expression and thereby affects developmental processes. It is also implicated in human diseases. This review explores the relationship between structural, biochemical and biophysical aspects of eIF4E and its function in vivo, including both long-established roles in translation and newly emerging ones in nuclear export and mRNA decay pathways.

Item Type: Article
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences > Protein Science Group
Depositing User: Tobias von der Haar
Date Deposited: 09 Sep 2008 15:12
Last Modified: 11 Jun 2014 10:41
Resource URI: http://kar.kent.ac.uk/id/eprint/5337 (The current URI for this page, for reference purposes)
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