Gullick, W.J. (2002) A new model for ductal carcinoma in situ suggests strategies for treatment. Breast Cancer Research, 4 (5). pp. 176-178. ISSN 1465-5411 .
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| Official URL http://dx.doi.org/10.1186/bcr447 |
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Abstract
Human ductal carcinoma in situ (DCIS) of the breast is now diagnosed quite frequently, due largely to the introduction of mammographic screening. It has been shown in a cell culture system that activation of c-erbB-2, but not the epidermal growth factor receptor, results in a DCIS-like phenotype. Since overexpression of c-erbB-2 occurs in 60% of DCIS, this suggests that it could be a target for treatment in this disease.
| Item Type: | Article |
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| Additional information: | Free full-text article in PubMed Central and on Breast Cancer Research. |
| Uncontrolled keywords: | ductal carcinoma in situ, growth factor receptor, tyrosine kinase inhibitor |
| Subjects: | Q Science R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculties > Science Technology and Medical Studies > School of Biosciences > Biomedical Research Group |
| Depositing User: | Bill Gullick |
| Date Deposited: | 04 Sep 2008 14:11 |
| Last Modified: | 05 Sep 2011 23:34 |
| Resource URI: | http://kar.kent.ac.uk/id/eprint/3986 (The current URI for this page, for reference purposes) |
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