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Valproic acid interferes with antiviral treatment in human cytomegalovirus-infected endothelial cells

Michaelis, Martin, Ha, T. Anh T., Doerr, Hans Wilhelm, Cinatl, Jindrich (2007) Valproic acid interferes with antiviral treatment in human cytomegalovirus-infected endothelial cells. Cardiovascular Research, 77 (3). pp. 544-550. ISSN 0008-6363. (doi:10.1093/cvr/cvm061) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:31385)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL:
http://dx.doi.org/10.1093/cvr/cvm061

Abstract

The endothelium represents a natural site of human cytomegalovirus (HCMV) infection involved in viral spreading and persistence. Moreover, HCMV infection of endothelial cells has been associated with different pathological conditions of the cardiovascular system. Here, the influence of the antiepileptic drug valproic acid (VPA) was investigated on HCMV replication in human umbilical vein endothelial cells alone or in combination with the antiviral drugs ganciclovir, cidofovir or foscarnet.

Item Type: Article
DOI/Identification number: 10.1093/cvr/cvm061
Uncontrolled keywords: Human cytomegalovirus; Antiviral therapy; Endothelium
Subjects: Q Science
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Susan Davies
Date Deposited: 08 Oct 2012 13:50 UTC
Last Modified: 16 Nov 2021 10:09 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/31385 (The current URI for this page, for reference purposes)

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