Electrophysiological recordings from the Drosophila giant fiber system (GFS).

Allen, Marcus J. and Godenschwege, Tanja A. (2010) Electrophysiological recordings from the Drosophila giant fiber system (GFS). Cold Spring Harbor Protocols, 2010 (8). ISSN 1559-6095. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1101/pdb.prot5453

Abstract

INTRODUCTION: The giant fiber system (GFS) of Drosophila is a well-characterized neuronal circuit that mediates the escape response in the fly. It is one of the few adult neural circuits from which electrophysiological recordings can be made routinely. This protocol describes a simple procedure for stimulating the giant fiber neurons directly in the brain of the adult fly and obtaining recordings from the output muscles of the GFS: the tergotrochanteral "jump" muscle (TTM) and the large indirect flight muscles (dorsal longitudinal muscles, or DLMs). It is a relatively noninvasive method that allows the investigator to stimulate the giant fibers in the brain and assay the function of several central synapses within this neural circuit by recording from the thoracic musculature.

Item Type: Article
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: Sue Davies
Date Deposited: 29 Jun 2011 15:37
Last Modified: 16 Apr 2014 13:47
Resource URI: http://kar.kent.ac.uk/id/eprint/26283 (The current URI for this page, for reference purposes)
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