Determining the parametric structure of models

Cole, D.J. and Morgan, B.J.T. and Titterington, D.M (2010) Determining the parametric structure of models. Mathematical Biosciences , 228 (1). pp. 16-30. ISSN 0025-5564. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1016/j.mbs.2010.08.004

Abstract

In this paper we develop a comprehensive approach to determining the parametric structure of models. This involves considering whether a model is parameter redundant or not and investigating model identifiability. The approach adopted makes use of exhaustive summaries, quantities that uniquely define the model. We review and generalise previous work on evaluating the symbolic rank of an appropriate derivative matrix to detect parameter redundancy, and then develop further tools for use within this framework, based on a matrix decomposition. Complex models, where the symbolic rank is difficult to calculate, may be simplified structurally using reparameterisation and by finding a reduced-form exhaustive summary. The approach of the paper is illustrated using examples from ecology, compartment modelling and Bayes networks. This work is topical as models in the biosciences and elsewhere are becoming increasingly complex.

Item Type: Article
Subjects: Q Science > QA Mathematics (inc Computing science) > QA276 Mathematical statistics
Divisions: Faculties > Science Technology and Medical Studies > School of Mathematics Statistics and Actuarial Science > Statistics
Depositing User: Diana Cole
Date Deposited: 26 Oct 2010 13:23
Last Modified: 02 Dec 2011 12:41
Resource URI: http://kar.kent.ac.uk/id/eprint/25925 (The current URI for this page, for reference purposes)
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