Popescu, D.C. and Lems, R. and Rossi, N.A.A. and Yeoh, C.T. and Loos, J. and Holder, S.J. and Bouten, C.V.C. and Sommerdijk, Najm (2005) The patterning and alignment of muscle cells using the selective adhesion of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers. Advanced Materials, 17 (19). 2324-+. ISSN 0935-9648.
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The selective adhesion/delamination behavior of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers is exploited to generate patterned substrates consisting of alternating lanes of glass and copolymer-coated gold. These patterns have been successfully used for the patterning and alignment of C2C12 muscle cells. The parallel-oriented myotubes (see Figure) contract upon electrical stimulation, forming a promising 2D in-vitro model for muscles.
|Additional information:||42 WILEY-V C H VERLAG GMBH|
|Subjects:||Q Science > QD Chemistry|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Physical Sciences > Functional Materials Group|
|Depositing User:||Simon Holder|
|Date Deposited:||29 Aug 2008 15:01|
|Last Modified:||05 Dec 2011 12:59|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/2563 (The current URI for this page, for reference purposes)|
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