The patterning and alignment of muscle cells using the selective adhesion of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers

Popescu, Daniela C. and Lems, R. and Rossi, Nicholas A. A. and Yeoh, Chert-Tsun and Loos, J. and Holder, Simon J. and Bouten, C.V.C. and Sommerdijk, Najm (2005) The patterning and alignment of muscle cells using the selective adhesion of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers. Advanced Materials, 17 (19). 2324-+. ISSN 0935-9648. (The full text of this publication is not available from this repository)

The full text of this publication is not available from this repository. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1002/adma.200500039

Abstract

The selective adhesion/delamination behavior of poly(oligoethylene glycol methyl ether methacrylate)-based ABA block copolymers is exploited to generate patterned substrates consisting of alternating lanes of glass and copolymer-coated gold. These patterns have been successfully used for the patterning and alignment of C2C12 muscle cells. The parallel-oriented myotubes (see Figure) contract upon electrical stimulation, forming a promising 2D in-vitro model for muscles.

Item Type: Article
Additional information: 42 WILEY-V C H VERLAG GMBH
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Science Technology and Medical Studies > School of Physical Sciences > Functional Materials Group
Depositing User: Simon Holder
Date Deposited: 29 Aug 2008 15:01
Last Modified: 22 May 2014 10:21
Resource URI: http://kar.kent.ac.uk/id/eprint/2563 (The current URI for this page, for reference purposes)
  • Depositors only (login required):