Does obesity compromise survival in women with breast cancer?

Carmichael, Amtul R and Bendall, Susan and Lockerbie, Lona and Prescott, R.J. and Bates, Tom (2004) Does obesity compromise survival in women with breast cancer? The Breast, 13 . pp. 93-96. (Access to this publication is restricted)

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Abstract

Summary Obesity, measured by high body mass index (BMI430 kg/m2) is associated with an increased risk of postmenopausal breast cancer but the effect of obesity on prognosis is not clear. A prospectively accrued and regularly validated database of 1579 patients with breast cancer treated in a district general hospital between 1963 and 1999 was analysed for clinical and pathological tumour characteristics including the family history, grade, tumour type, treatment and outcome. The risk factors and outcome of obese and non-obese patients were compared. Breast cancer in obese women was associated with significantly larger tumour size and worse Nottingham prognostic index. There was no statistically significant difference in overall and disease-free survival between obese and nonobese group. Hazard ratios (95% Cl) were 0.81 (0.62–1.06) and 0.80 (0.63–1.01), respectively. In the present study, obesity is not an indicator of worst prognosis of breast cancer.

Item Type: Article
Subjects: R Medicine > RD Surgery
R Medicine
Divisions: Faculties > Social Sciences > Centre for Professional Practice
Depositing User: Tom Bates
Date Deposited: 29 Jun 2011 13:20
Last Modified: 27 Jun 2014 14:18
Resource URI: http://kar.kent.ac.uk/id/eprint/23630 (The current URI for this page, for reference purposes)
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