Bates, T. and Antoniou, A. and Marshall, R.E.K. and Harrison, M. and Bassett, E.E. (2008) The Changing Management of Oesophageal Carcinoma: Survival in a Population Cohort 1985-1994. The Open Clinical Cancer Journal, 2 . pp. 44-50. ISSN 1874-1894 .
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Abstract: Background: The management of esophageal carcinoma is changing but before the introduction of chemotherapy and multidisciplinary teams, surgery became more selective. The aim of this study was to confirm this trend and to examine survival in a total population cohort 1985-94. Results: Only a quarter of 413 patients had surgery but from 1989 even fewer were operated on but there were more longterm survivors: 1/51 v. 7/58 (p<0.05). Operative mortality fell from 12% to 6.9 % in the later period (N.S.) and survival post surgery was marginally improved, 15 v. 11 months p = 0.0502. The five year survival rate doubled from 7.8% to 17.2%. Conclusion: Few studies of esophageal cancer include all cases in a defined population. This carries a very poor prognosis but the present cohort shows a slight improvement with more selective surgery and this may serve as a benchmark against which modern multidisciplinary management might be compared. Keywords: Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis.
|Uncontrolled keywords:||Esophageal cancer, Esophagectomy, Radiotherapy, Mortality, Prognosis|
|Subjects:||R Medicine > RD Surgery
|Divisions:||Faculties > Science Technology and Medical Studies > School of Mathematics Statistics and Actuarial Science
Faculties > Social Sciences > Centre for Professional Practice
|Depositing User:||Tom Bates|
|Date Deposited:||24 Feb 2010 10:47|
|Last Modified:||06 Sep 2011 04:42|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/23626 (The current URI for this page, for reference purposes)|
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