Magnani, M. and Galluzzi, L. and Bruce, I.J. (2006) The use of magnetic nanoparticles in the development of new molecular detection systems. Journal of Nanoscience and Nanotechnology, 6 (8). pp. 2302-2311. ISSN 1533-4880 .
|The full text of this publication is not available from this repository. (Contact us about this Publication)|
Magnetic nanoparticles have been widely used in biomolecular separation and discrimination which coincidentally also represents the basis for most current day molecular diagnostic procedures. The specificity, affinity, and binding capacity of magnetic nanoparticles depends on their size, form, dispersion, and surface chemistry. In this review, we will briefly analyze how these factors affect biomolecular separations and focus on the use of magnetic nanoparticles in monitoring the microbial biodiversity in the environment. We found that magnetic nanoparticles are especially effective for biomolecular separations in environmental samples collected and preserved with fixatives. This feature, together with the high sample throughput capability and the generic low cost, makes magnetic nanoparticles particularly suitable for environmental microbial monitoring. Furthermore, key features that permit the optimization of magnetic nanoparticles-based separations and that can be useful in the development of new analytical procedures are also discussed.
|Uncontrolled keywords:||magnetic nanoparticles; detection; environment|
|Subjects:||Q Science > QD Chemistry
Q Science > QC Physics
|Divisions:||Faculties > Science Technology and Medical Studies > School of Biosciences|
|Depositing User:||Suzanne Duffy|
|Date Deposited:||11 Sep 2009 14:06|
|Last Modified:||11 Sep 2009 14:06|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/22815 (The current URI for this page, for reference purposes)|
- Depositors only (login required):