Gourlay, C.W. and Ayscough, K.R. (2005) The actin cytoskeleton: a key regulator of apoptosis and ageing? Nature Reviews Molecular Cell Biology, 6 (7). pp. 583-589.
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| Official URL http://dx.doi.org/10.1038/nrm1682 |
Abstract
Evidence from many organisms has shown that the accumulation of reactive oxygen species (ROS) has a detrimental effect on cell well-being. High levels of ROS have been linked to programmed cell death pathways and to ageing. Recent reports have implicated changes to the dynamics of the actin cytoskeleton in the release of ROS from mitochondria and subsequent cell death.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculties > Science Technology and Medical Studies > School of Biosciences |
| Depositing User: | Campbell Gourlay |
| Date Deposited: | 29 Sep 2009 16:12 |
| Last Modified: | 17 Apr 2012 14:11 |
| Resource URI: | http://kar.kent.ac.uk/id/eprint/22643 (The current URI for this page, for reference purposes) |
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