The actin cytoskeleton: a key regulator of apoptosis and ageing?

Gourlay, Campbell W. and Ayscough, Kathryn R. (2005) The actin cytoskeleton: a key regulator of apoptosis and ageing? Nature Reviews Molecular Cell Biology, 6 (7). pp. 583-589. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1038/nrm1682

Abstract

Evidence from many organisms has shown that the accumulation of reactive oxygen species (ROS) has a detrimental effect on cell well-being. High levels of ROS have been linked to programmed cell death pathways and to ageing. Recent reports have implicated changes to the dynamics of the actin cytoskeleton in the release of ROS from mitochondria and subsequent cell death.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: Campbell Gourlay
Date Deposited: 29 Sep 2009 16:12
Last Modified: 16 Jun 2014 10:51
Resource URI: http://kar.kent.ac.uk/id/eprint/22643 (The current URI for this page, for reference purposes)
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