Apoptosis in yeast--mechanisms and benefits to a unicellular organism.

Gourlay, Campbell W. and Du, W. and Ayscough, K.R. (2006) Apoptosis in yeast--mechanisms and benefits to a unicellular organism. Molecular Microbiology, 62 (6). pp. 1515-1521. ISSN 0950-382X . (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1111/j.1365-2958.2006.05486.x

Abstract

Initial observations that the budding yeast Saccharomyces cerevisiae can be induced to undergo a form of cell death exhibiting typical markers of apoptosis has led to the emergence of a thriving new field of research. Since this discovery, a number of conserved pro- and antiapoptotic proteins have been identified in yeast. Indeed, early experiments have successfully validated yeasts as a powerful genetic tool with which to investigate mechanisms of apoptosis. However, we still have little understanding as to why programmes of cell suicide exist in unicellular organisms and how they may be benefit such organisms. Recent research has begun to elucidate pathways that regulate yeast apoptosis in response to environmental stimuli. These reports strengthen the idea that physiologically relevant mechanisms of programmed cell death are present, and that these function as important regulators of yeast cell populations.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: Campbell Gourlay
Date Deposited: 29 Sep 2009 15:18
Last Modified: 09 Aug 2013 08:06
Resource URI: http://kar.kent.ac.uk/id/eprint/22639 (The current URI for this page, for reference purposes)
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