Tuite, M.F. (1992) Antifungal drug development - the identification of new targets. Trends in Biotechnology, 10 (7). pp. 235-239. ISSN 0167-7799.
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Abstract
With the increasing prevalence of life-threatening systemic fungal infections in the human population, there is a need to develop new, more-effective antifungal agents. This, in turn, will depend upon the identification and exploitation of new antifungal targets - aspects of fungal cytology, metabolism and gene expression which are important for fungal pathogenesis, but which have no mammalian host counterpart. Such new targets have been identified through a combination of classical genetic, cytological and biochemical studies and are reviewed here, as is the potential for applying recombinant DNA techniques as a means of confirming the role of the identified gene products in pathogenesis.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculties > Science Technology and Medical Studies > School of Biosciences |
| Depositing User: | O.O. Odanye |
| Date Deposited: | 27 Jul 2009 22:33 |
| Last Modified: | 13 Mar 2012 09:41 |
| Resource URI: | http://kar.kent.ac.uk/id/eprint/22260 (The current URI for this page, for reference purposes) |
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