Homology modelling of haloalkane dehalogenase of Sfingomonas paucimobilis UT26

Damborsky, Jiri and Bull, Alan T. and Hardman, David J. (1995) Homology modelling of haloalkane dehalogenase of Sfingomonas paucimobilis UT26. Biologia, 50 (6). pp. 523-528. ISSN 0006-3088. (The full text of this publication is not available from this repository)

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Abstract

The hypothetical three-dimensional structure of the enzyme 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase isolated from the strain Sfingomonas paucimobilis UT26 was modelled. Hydrolytic dehalogenase from another bacterial strain (Xanthobacter autotrophicus GJ10), previously studied by X-ray analysis, was used as a reference structure. Differences between the residues in the active site cavity of both enzymes have been related to their substrate activity.

Item Type: Article
Uncontrolled keywords: haloalkane dehalogenase; microbial dehalogenation; homology modelling; structure-function relationships
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences > Cell & Developmental Biology Group
Depositing User: P. Ogbuji
Date Deposited: 03 Jun 2009 15:32
Last Modified: 16 Apr 2014 11:01
Resource URI: http://kar.kent.ac.uk/id/eprint/19798 (The current URI for this page, for reference purposes)
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