Minelly, S. and Kelly, S.W. and Bahra, R. (1996) Clinical trial of the non-invasive recording of His-Purkinje system signals. In: 23rd Annual Scientific Meeting on Computers in Cardiology, Sep 08-11, 1996, Indianapolis, In.
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| Official URL http://dx.doi.org/10.1109/CIC.1996.542570 |
Abstract
A clinical system has been developed to detect His-Purkinje System (HPS) signals using surface recording technology and ensemble averaging. The reproducibility of this non-invasive methodology for recording Hisbundle signals in normal human volunteers has been. tested in a controlled clinical environment. The study recorded HPS signals from eight healthy volunteers, undosed, on placebo and following a single dose of beta-blocker (atenolol). This allowed the effects of the atenolol on the His-bundle intervals to be observed in a controlled fashion. A late notch (H) is recorded about 15ms before ventricular activation for most subjects in both dosed and un-dosed conditions. However in some subjects there is a distinct increase in the A-H interval with atenolol. This indicates that the H-notch originates from the conduction system.
| Item Type: | Conference or workshop item (Paper) |
|---|---|
| Subjects: | T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800 Electronics (see also: telecommunications) > TK7880 Applications of electronics (inc industrial & domestic) Q Science > QA Mathematics (inc Computing science) > QA 75 Electronic computers. Computer science T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | Faculties > Science Technology and Medical Studies > School of Engineering and Digital Arts |
| Depositing User: | F.D. Zabet |
| Date Deposited: | 22 Jun 2009 10:55 |
| Last Modified: | 22 Jun 2009 10:55 |
| Resource URI: | http://kar.kent.ac.uk/id/eprint/18696 (The current URI for this page, for reference purposes) |
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