Clinical trial of the non-invasive recording of His-Purkinje system signals

Minelly, S. and Kelly, S.W. and Bahra, R. (1996) Clinical trial of the non-invasive recording of His-Purkinje system signals. In: 23rd Annual Scientific Meeting on Computers in Cardiology, Sep 08-11, 1996, Indianapolis, In. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1109/CIC.1996.542570

Abstract

A clinical system has been developed to detect His-Purkinje System (HPS) signals using surface recording technology and ensemble averaging. The reproducibility of this non-invasive methodology for recording Hisbundle signals in normal human volunteers has been. tested in a controlled clinical environment. The study recorded HPS signals from eight healthy volunteers, undosed, on placebo and following a single dose of beta-blocker (atenolol). This allowed the effects of the atenolol on the His-bundle intervals to be observed in a controlled fashion. A late notch (H) is recorded about 15ms before ventricular activation for most subjects in both dosed and un-dosed conditions. However in some subjects there is a distinct increase in the A-H interval with atenolol. This indicates that the H-notch originates from the conduction system.

Item Type: Conference or workshop item (Paper)
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800 Electronics (see also: telecommunications) > TK7880 Applications of electronics (inc industrial & domestic)
Q Science > QA Mathematics (inc Computing science) > QA 75 Electronic computers. Computer science
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Faculties > Science Technology and Medical Studies > School of Engineering and Digital Arts
Depositing User: F.D. Zabet
Date Deposited: 22 Jun 2009 10:55
Last Modified: 22 Jun 2009 10:55
Resource URI: http://kar.kent.ac.uk/id/eprint/18696 (The current URI for this page, for reference purposes)
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