A synthesis of alpha,alpha-disubstituted aryl-beta-ketoesters

Stefaniak, M.H. and Tinardon, F. and Wallis, John D. (1997) A synthesis of alpha,alpha-disubstituted aryl-beta-ketoesters. Synlett (6). pp. 677-678. ISSN 0936-5214. (The full text of this publication is not available from this repository)

The full text of this publication is not available from this repository. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1055/s-1997-3249

Abstract

A generally applicable synthesis of alpha,alpha-disubstituted beta-ketoesters involving reaction of a substituted benzoyl chloride with methyl trimethylsilyl ketene acetal is described. Addition of boron trifluoride etherate is essential when the benzoyl chloride is nor substituted with a strongly electron withdrawing residue. The majority of experiments were conducted with the dimethylketene acetal but the process is equally applicable to the cyclohexaneketene acetal 5.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Science Technology and Medical Studies > School of Physical Sciences
Depositing User: T.J. Sango
Date Deposited: 12 May 2009 09:03
Last Modified: 12 May 2009 09:03
Resource URI: http://kar.kent.ac.uk/id/eprint/17973 (The current URI for this page, for reference purposes)
  • Depositors only (login required):