Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes

Dearling, Jason L. J. and Lewis, Jason S. and McCarthy, D.W. and Welch, Michael J. and Blower, Philip J. (1998) Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes. Chemical Communications (22). pp. 2531-2532. ISSN 1359-7345. (The full text of this publication is not available from this repository)

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Official URL
http://dx.doi.org/10.1039/a805957h

Abstract

Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: R.F. Xu
Date Deposited: 01 May 2009 16:45
Last Modified: 11 Jun 2014 13:48
Resource URI: http://kar.kent.ac.uk/id/eprint/17692 (The current URI for this page, for reference purposes)
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