Dearling, J.L.J. and Lewis, J.S. and McCarthy, D.W. and Welch, M.J. and Blower, P.J. (1998) Redox-active metal complexes for imaging hypoxic tissues: structure-activity relationships in copper(II) bis(thiosemicarbazone) complexes. Chemical Communications (22). pp. 2531-2532. ISSN 1359-7345.
| The full text of this publication is not available from this repository. (Contact us about this Publication) | |
| Official URL http://dx.doi.org/10.1039/a805957h |
Abstract
Reduction potential and lipophilicity of the copper(II) bis(thiosemicarbazone) complexes can be independently controlled by alkylation in the diketone backbone and the N-termini of the ligand, allowing optimisation of radiopharmaceuticals strongly selective for hypoxic tissues.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculties > Science Technology and Medical Studies > School of Biosciences |
| Depositing User: | R.F. Xu |
| Date Deposited: | 01 May 2009 16:45 |
| Last Modified: | 01 May 2009 16:45 |
| Resource URI: | http://kar.kent.ac.uk/id/eprint/17692 (The current URI for this page, for reference purposes) |
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