B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse

Cook, C.C.H. and Hallwood, P.M. and Thomson, A.D. (1998) B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol and Alcoholism, 33 (4). pp. 317-36. ISSN 0735-0414. (The full text of this publication is not available from this repository)

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Abstract

Alcohol misuse and alcohol withdrawal are associated with a variety of neuropsychiatric syndromes, some of which are associated with significant morbidity and mortality. B vitamin deficiency is known to contribute to the aetiology of a number of these syndromes, and B vitamin supplementation thus plays a significant part in prophylaxis and treatment. In particular, the Wernicke-Korsakoff syndrome (WKS), due to thiamine deficiency, ij a common condition in association with alcohol misuse, and is associated with high morbidity and mortality. Nicotinamide deficiency may result in a rarer condition, alcoholic pellagra encephalopathy, which often has a similar clinical presentation to WKS. This review considers the role of B vitamins in the aetiology and treatment of neuropsychiatric syndromes associated with alcohol misuse, with particular emphasis on WKS.

Item Type: Article
Subjects: R Medicine
Divisions: Faculties > Science Technology and Medical Studies > Kent Institute of Medicine and Health Sciences (KIMHS)
Depositing User: I. Ghose
Date Deposited: 02 Apr 2009 18:34
Last Modified: 02 Apr 2009 18:34
Resource URI: http://kar.kent.ac.uk/id/eprint/17657 (The current URI for this page, for reference purposes)
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