Cook, C.C.H. and Hallwood, P.M. and Thomson, A.D. (1998) B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol and Alcoholism, 33 (4). pp. 317-36. ISSN 0735-0414.
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Alcohol misuse and alcohol withdrawal are associated with a variety of neuropsychiatric syndromes, some of which are associated with significant morbidity and mortality. B vitamin deficiency is known to contribute to the aetiology of a number of these syndromes, and B vitamin supplementation thus plays a significant part in prophylaxis and treatment. In particular, the Wernicke-Korsakoff syndrome (WKS), due to thiamine deficiency, ij a common condition in association with alcohol misuse, and is associated with high morbidity and mortality. Nicotinamide deficiency may result in a rarer condition, alcoholic pellagra encephalopathy, which often has a similar clinical presentation to WKS. This review considers the role of B vitamins in the aetiology and treatment of neuropsychiatric syndromes associated with alcohol misuse, with particular emphasis on WKS.
|Divisions:||Faculties > Science Technology and Medical Studies > Kent Institute of Medicine and Health Sciences (KIMHS)|
|Depositing User:||I. Ghose|
|Date Deposited:||02 Apr 2009 18:34|
|Last Modified:||02 Apr 2009 18:34|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/17657 (The current URI for this page, for reference purposes)|
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