Copello, A. and Godfrey, C. and Heather, N. and Hodgson, R. and Orford, J. and Raistrick, C. and Russell, I. and Tober, G. and Slegg, G.P. and Alwyn, T. and Kerr, C. and Thistlethwaite, G. and Barrett, C. and Kenyon, R. and Carlyle, K. and Gillam, R. and Handforth, L. and John, B. and Smith, M. and Coulton, S. and Farrin, A. and Parrott, S. and Chalk, P. and Champney-Smith, J. and Crome, I. and Emlyn-Jones, R. and Fleming, A. and Kahn, A. and McBride, A. and Parkes, S. and Summers, Z. and Williams, P. (2001) United Kingdom Alcohol Treatment Trial (UKATT): Hypotheses, design and methods. Alcohol and Alcoholism, 36 (1). pp. 11-21. ISSN 0735-0414.
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The United Kingdom Alcohol Treatment Trial (UKATT) is intended to be the largest trial of treatment for alcohol problems ever conducted in the UK. UKATT is a multicentre, randomized, controlled trial with blind assessment, representing a collaboration between psychiatry, clinical psychology, biostatistics, and health economics. This article sets out, in advance of data analysis, the theoretical background of the trial and its hypotheses, design, and methods. A projected total of 720 clients attending specialist services for treatment of alcohol problems will be randomized to Motivational Enhancement Therapy (MET) or to Social Behaviour and Network Therapy (SBNT), a novel treatment developed for the trial with strong support from theory and research. The trial will test two main hypotheses, expressed in null form as: (1) less intensive, motivationally based treatment (MET) is as effective as more intensive, socially based treatment (SBNT); (2) more intensive, socially based treatment (SBNT) is as cost-effective as less intensive, motivationally based treatment (MET). A number of subsidiary hypotheses regarding client-treatment interactions and therapist effects will also be tested. The article describes general features of the trial that investigators considered desirable, namely that it should: (1) be a pragmatic, rather than an explanatory, trial; (2) be an effectiveness trial based on 'real-world' conditions of treatment delivery; (3) incorporate high standards of training, supervision and quality control of treatment delivery; (4) pay close attention to treatment process as well as treatment outcome; (5) build economic evaluation into the design at the outset. First results from UKATT are expected in 2002 and the main results in 2003.
|Additional information:||Times Cited: 25|
|Subjects:||R Medicine > R Medicine (General)
B Philosophy. Psychology. Religion > BF Psychology
|Divisions:||Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies|
|Depositing User:||Simon Coulton|
|Date Deposited:||07 Apr 2009 14:45|
|Last Modified:||12 Jun 2012 10:32|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/16970 (The current URI for this page, for reference purposes)|
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