Simone, M.L. and Edwards, Alison A. and Tranter, George E. and Fleet, George W.J. Carbon-branched delta-tetrahydrofuran sugar amino acids (SAAs) as dipeptide isostere scaffolds. Tetrahedron .
PDF (2008 Tetrahedron C-2 branched SAA monomers)
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The synthesis of the first branched sugar amino acid (SAA) scaffolds [methyl (3R,4R,5R)-5-azidomethyl- 3,4-dihydroxy-tetrahydrofuran-3-carboxylate and methyl (3R,4R,5S)-5-azidomethyl-3,4-dihydroxy-tetrahydrofuran- 3-carboxylate] by an efficient intramolecular displacement of a highly hindered neopentyl triflate allows access to enantiopure THF derivatives which have carbon substituents.
|Subjects:||Q Science > QD Chemistry|
|Divisions:||Faculties > Science Technology and Medical Studies > Medway School of Pharmacy|
|Depositing User:||Alison Edwards|
|Date Deposited:||29 Jun 2011 07:46|
|Last Modified:||28 May 2012 10:46|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/16775 (The current URI for this page, for reference purposes)|
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