Senior, J. and Rolland, D. and Tolson, D. and Chantzis, S. and De Biasi, V. (2000) The analysis of basic and acidic compounds using non-aqueous CE and non-aqueous CE-MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS , 22 (3). pp. 413-421. ISSN 0731-7085 .
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It has been shown that non-aqueous capillary electrophoresis (NACE) can provide improved separations in comparison to those obtained using conventional CE under aqueous conditions  (ACE). Previous work carried out in our laboratories involving initial investigations into the technique have been reported . Based on the findings of that work it was possible to separate a variety of basic pharmaceuticals from selected impurities and to obtain the successful separation of some hydrophobic sulphonic acids. The successful coupling of NACE to mass spectrometry (NACE-MS) has also been demonstrated. (C) 2000 Elsevier Science B.V. All rights reserved.
|Additional information:||10th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 99) WASHINGTON, D.C., MAY 09-12, 1999|
|Uncontrolled keywords:||non-aqueous capillary electrophoresis; non-aqueous capillary electrophoresis-mass spectrometry; compounds|
|Subjects:||Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
|Depositing User:||A. Xie|
|Date Deposited:||07 Sep 2009 13:02|
|Last Modified:||07 Sep 2009 13:02|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/16624 (The current URI for this page, for reference purposes)|
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