The analysis of basic and acidic compounds using non-aqueous CE and non-aqueous CE-MS

Senior, J. and Rolland, D. and Tolson, D. and Chantzis, S. and De Biasi, V. (2000) The analysis of basic and acidic compounds using non-aqueous CE and non-aqueous CE-MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS , 22 (3). pp. 413-421. ISSN 0731-7085 . (The full text of this publication is not available from this repository)

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Abstract

It has been shown that non-aqueous capillary electrophoresis (NACE) can provide improved separations in comparison to those obtained using conventional CE under aqueous conditions [1] (ACE). Previous work carried out in our laboratories involving initial investigations into the technique have been reported [2]. Based on the findings of that work it was possible to separate a variety of basic pharmaceuticals from selected impurities and to obtain the successful separation of some hydrophobic sulphonic acids. The successful coupling of NACE to mass spectrometry (NACE-MS) has also been demonstrated. (C) 2000 Elsevier Science B.V. All rights reserved.

Item Type: Article
Additional information: 10th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 99) WASHINGTON, D.C., MAY 09-12, 1999
Uncontrolled keywords: non-aqueous capillary electrophoresis; non-aqueous capillary electrophoresis-mass spectrometry; compounds
Subjects: Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
Depositing User: A. Xie
Date Deposited: 07 Sep 2009 13:02
Last Modified: 07 Sep 2009 13:02
Resource URI: http://kar.kent.ac.uk/id/eprint/16624 (The current URI for this page, for reference purposes)
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