Emergence of Uptake Signals in Bacterial DNA

Chu, Dominique and Lee, H.C. and Lenaerts, T. (2005) Emergence of Uptake Signals in Bacterial DNA. Artificial Life, 11 (3). pp. 317-338. (The full text of this publication is not available from this repository)

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Abstract

The DNA of some naturally competent species of bacteria contains a large number of evenly distributed copies of a short (about 10bp long) sequence. This highly overrepresented sequence is believed to be an uptake signal sequence (USS) that helps bacteria to take up DNA selectively from (dead) members of their own species. For some time it has been assumed that the USS evolved in order to enable bacteria to distinguish between conspecific and non-conspecific DNA fragments (the preference-first hypothesis). Recently, Redfield suggested that this hypothesis is not in fact realistic, as it would require biologically implausible group selection. In this article we present a model designed to demonstrate the emergence of similar USSs in a population of simulated evolving agents. We use this model to examine the conditions under which a USS will emerge in a preference-first scenario.

Item Type: Article
Subjects: Q Science > QA Mathematics (inc Computing science) > QA 76 Software, computer programming,
Divisions: Faculties > Science Technology and Medical Studies > School of Computing > Applied and Interdisciplinary Informatics Group
Depositing User: Dominique Chu
Date Deposited: 24 Nov 2008 18:03
Last Modified: 04 Dec 2013 09:51
Resource URI: http://kar.kent.ac.uk/id/eprint/14370 (The current URI for this page, for reference purposes)
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