Individual-based simulation of the clustering behaviour of epidermal growth factor receptors

Goldman, Jacki P. and Gullick, William J. and Bray, D. and Johnson, Colin G. (2002) Individual-based simulation of the clustering behaviour of epidermal growth factor receptors. In: Proceedings of the 2002 ACM Symposium on Applied Computing, March 11 - 14, 2002, Madrid, Spain. (Full text available)

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Official URL
http://dx.doi.org/10.1145/508791.508817

Abstract

This paper describes ongoing work on a project to simulate the behaviour of epidermal growth factor receptors. These are structures which can be found on the surface of cells in the body, which receive and process chemical signals concerned with cell growth. We describe the implementation of a program which simulates the stimulation and clustering behaviour of these structures, discuss how we scale up this simulation so that we can simulate a whole cell on a tractable timescale, and discuss ongoing work in which we are calibrating our simulation against results from experiments.

Item Type: Conference or workshop item (Paper)
Uncontrolled keywords: computational biology, simulation, modelling, receptor biology, cancer
Subjects: Q Science > QA Mathematics (inc Computing science) > QA 76 Software, computer programming,
Divisions: Faculties > Science Technology and Medical Studies > School of Computing > Applied and Interdisciplinary Informatics Group
Depositing User: Mark Wheadon
Date Deposited: 24 Nov 2008 18:00
Last Modified: 21 May 2014 13:32
Resource URI: http://kar.kent.ac.uk/id/eprint/13817 (The current URI for this page, for reference purposes)
ORCiD (Goldman, Jacki P.):
ORCiD (Gullick, William J.):
ORCiD (Bray, D.):
ORCiD (Johnson, Colin G.):
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