Quilter, C.R. and Wood, D. and Southwood, O.I. and Griffin, D.K. (2003) X/XY/XYY mosaicism as a cause of subfertility in boars: a single case study. Animal Genetics, 34 (1). pp. 51-54. ISSN 0268-9146 .
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Sex chromosome abnormalities are common in mammals and humans and are often associated with subfertility. In this study a boar with normal sperm parameters was indicated to have reduced prolificacy from figures obtained for return rate, farrowing rate and total number of piglets born. G-banded cytogenetic analysis of peripheral blood identified an abnormal mosaic sex chromosome constitution 39,XYY/38,XY/37,X. Cytogenetic analysis of fibroblasts confirmed this mosaic karyotype with similar percentages of cell lines observed 39,XYY/38,XY/37,X. External genitalia revealed a poorly developed scrotum with the right testicle being smaller than the left. To the best of our knowledge this is the first time that this chromosome constitution has been reported in the pig. It is of particular interest that this karyotype is associated with reduced boar fertility, which could lead to potential economic losses if such a boar were selected for breeding purposes.
|Additional information:||12580787 0268-9146|
|Uncontrolled keywords:||Animals Breeding Cytogenetic Analysis Fertility Karyotyping Male Mosaicism Sex Chromosome Aberrations Swine Y Chromosome|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Biosciences|
|Depositing User:||Darren Griffin|
|Date Deposited:||10 Sep 2008 13:47|
|Last Modified:||03 Mar 2009 11:37|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/12481 (The current URI for this page, for reference purposes)|
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