Shibusawa, M. and Nishida-Umehara, C. and Masabanda, J. and Griffin, D.K. and Isobe, T. and Matsuda, Y. (2002) Chromosome rearrangements between chicken and guinea fowl defined by comparative chromosome painting and FISH mapping of DNA clones. Cytogenetic and Genome Research, 98 (2-3). pp. 225-230. ISSN 1424-8581.
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Chromosome homology between chicken (Gallus gallus) and guinea fowl (Numida meleagris) was investigated by comparative chromosome painting with chicken whole chromosome paints for chromosomes 1-9 and Z and by comparative mapping of 38 macrochromosome-specific (chromosomes 1-8 and Z) and 30 microchromosome-specific chicken cosmid DNA clones. The comparative chromosome analysis revealed that the homology of macrochromosomes is highly conserved between the two species except for two inter-chromosomal rearrangements. Guinea fowl chromosome 4 represented the centric fusion of chicken chromosome 9 with the q arm of chicken chromosome 4. Guinea fowl chromosome 5 resulted from the fusion of chicken chromosomes 6 and 7. A pericentric inversion was found in guinea fowl chromosome 7, which corresponded to chicken chromosome 8. All the chicken microchromosome-specific DNA clones were also localized to microchromosomes of guinea fowl except for several clones localized to the short arm of chromosome 4. These results suggest that the cytogenetic genome organization is highly conserved between chicken and guinea fowl.
|Additional information:||12698009 1424-8581|
|Uncontrolled keywords:||Animals Chickens Chromosome Mapping Chromosome Painting Chromosomes, Mammalian Cloning, Molecular DNA Evolution, Molecular Gene Rearrangement In Situ Hybridization, Fluorescence Karyotyping Poultry|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Biosciences|
|Depositing User:||Darren Griffin|
|Date Deposited:||23 Oct 2008 10:41|
|Last Modified:||03 Mar 2009 12:12|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/12473 (The current URI for this page, for reference purposes)|
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