Kuroiwa, A. and Uchikawa, M. and Kamachi, Y. and Kondoh, H. and Nishida-Umehara, C. and Masabanda, J. and Griffin, D.K. and Matsuda, Y. (2002) Chromosome assignment of eight SOX family genes in chicken. Cytogenetic and Genome Research, 98 (2-3). pp. 189-193. ISSN 1424-8581.
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Chromosome locations of the eight SOX family genes, SOX1, SOX2, SOX3, SOX5, SOX9, SOX10, SOX14 and SOX21, were determined in the chicken by fluorescence in situ hybridization. The SOX1 and SOX21 genes were localized to chicken chromosome 1q3.1-->q3.2, SOX5 to chromosome 1p1.6-->p1.4, SOX10 to chromosome 1p1.6, and SOX3 to chromosome 4p1.2-->p1.1. The SOX2 and SOX14 genes were shown to be linked to chromosome 9 using two-colored FISH and chromosome painting, and the SOX9 gene was assigned to a pair of microchromosomes. These results suggest that these SOX genes form at least three clusters on chicken chromosomes. The seven SOX genes, SOX1, SOX2, SOX3, SOX5, SOX10, SOX14 and SOX21 were localized to chromosome segments with homologies to human chromosomes, indicating that the chromosome locations of SOX family genes are highly conserved between chicken and human.
|Additional information:||12698002 1424-8581|
|Uncontrolled keywords:||Animals Chickens Chromosome Mapping Chromosome Painting Chromosomes, Mammalian DNA-Binding Proteins High Mobility Group Proteins HMGB Proteins Humans In Situ Hybridization, Fluorescence Neoplasm Proteins Nuclear Proteins Transcription Factors|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Biosciences|
|Depositing User:||Darren Griffin|
|Date Deposited:||24 Sep 2008 14:27|
|Last Modified:||03 Mar 2009 12:10|
|Resource URI:||http://kar.kent.ac.uk/id/eprint/12472 (The current URI for this page, for reference purposes)|
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