The brain in heart failure

Pullicino, P. (2004) The brain in heart failure. Malta Medical Journal, 16 (4). pp. 9-14. (The full text of this publication is not available from this repository)

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Abstract

After atrial fibrillation, heart failure is the second most frequent cardiac association of stroke. Deteriorating left ventricular systolic function appears to increase the risk of cardioembolic stroke in heart failure. Age, hypertension and prior stroke are also risk factors for stroke in heart failure. Since these are risk factors for cerebral and other vascular disease rather than for cardioembolism, embolism may not be the sole pathogenesis of stroke in heart failure. Hypoperfusion as a cause of cerebral injury is suggested by a reduction of blood flow and autoregulatory capacity in severe heart failure. An increase in cerebral infarct volume and impaired cognition in patients with left ventricular systolic dysfunction also supports this. There is a need for further research to define how the brain is affected by progressive cardiac failure and to determine which echocardiographic and other vascular risk factors best indicate an increased stroke risk.

Item Type: Article
Additional information: NOT IN FILE
Uncontrolled keywords: Heart failure, congestive, ventricular ejection fraction, brain ischemia, brain infarction, cognition
Subjects: R Medicine > R Medicine (General)
Divisions: Faculties > Science Technology and Medical Studies > Kent Institute of Medicine and Health Sciences (KIMHS)
Depositing User: M.P. Stone
Date Deposited: 28 May 2009 19:28
Last Modified: 28 May 2009 19:28
Resource URI: http://kar.kent.ac.uk/id/eprint/12238 (The current URI for this page, for reference purposes)
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