Theoretical modeling of oral absorption of barbiturates

Ghafourian, Taravat and Barzegar-Jalali, Mohammad (2002) Theoretical modeling of oral absorption of barbiturates. IL Farmaco, 57 (7). pp. 565-567. ISSN 0014-827X. (The full text of this publication is not available from this repository)

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Abstract

The structural characteristics governing gastric absorption of barbiturates were studied using QSAR methodology. The results showed that the gastric absorption rate constant could be modeled using the theoretical parameters, accessible surface area, atomic charges and electrostatic potentials. Using molecular connectivity indexes was also satisfactory in modeling the absorption. © 2002 E´ ditions scientifiques et me´dicales Elsevier SAS.

Item Type: Article
Uncontrolled keywords: absorption; QSAR; barbiturate; gastric; oral absorption
Subjects: Q Science
Q Science > QD Chemistry
Divisions: Faculties > Science Technology and Medical Studies > Medway School of Pharmacy
Depositing User: Taravat Ghafourian
Date Deposited: 17 Sep 2008 16:58
Last Modified: 20 May 2014 15:26
Resource URI: http://kar.kent.ac.uk/id/eprint/10763 (The current URI for this page, for reference purposes)
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